GeneTitan artifacts II

Friday, January 28th, 2011 by hinrich


I have previously discussed that the new Affymetrix GeneTitan system for generating whole genome transcriptional profiles in a 96-well plate likely has different artifacts than the regular cartridge arrays.

We have made a first version of a R library called TitanQC available via R-Forge. The package contains various functions to look into potential spatial effects on the 96-well plate. Graphics visualizing the individual intensity distributions per sample, median raw probe intensities, but also an overall image of individual affyPLM images ordered according to their respective position within the plate are included.

Please beware that the package is not yet finished. We still need to work on the documentation. You can find the home page of the project on R-Forge here.

Posted in Molecular Profiling